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For Patients & Caregivers

Search to find clinical trials that are of interest to you.

Research Areas

Cardiology

Physician researchers at Gagnon Cardiovascular Institute at Morristown Medical Center and Overlook Medical Center have established an enduring history in transforming cardiovascular care through a commitment to bringing the most advanced therapies and technologies to our communities. Through clinical trial participation, our cardiac research team is provided extensive experience with new, highly effective remedies prior to their full introduction into the marketplace.

Our cardiology, cardiovascular medicine and cardiac surgery departments participate in dozens of clinical trials each year. These national and international studies enhance our physicians' familiarity with promising advancements in electrophysiology, cardiac surgery, vascular surgery and clinical cardiology. The result: improved outcomes for our patients.

Trials are underway that assess the effectiveness of minimally invasive surgical techniques and devices, electrophysiology procedures, and medications.

Areas of Research Expertise

  • Coronary Artery Disease
  • Severe Aortic Stenosis
  • Mitral Valve Regurgitation
  • Atrial Fibrillation
  • Sudden Death Prevention & Heart Failure
  • Stroke
  • Peripheral Artery Disease
  • Hypertension (High Blood Pressure)
  • Familial Hypercholesterolemia
  • Venous Thromboembolism

Our Physician Researchers

Neuroscience

Atlantic Neuroscience Institute at Overlook Medical Center has made significant strides in recent years to make research a mainstay feature of the program's key services. Our physicians are conducting ongoing research to offer the most advanced diagnostic and therapeutic services available for stroke patients and those who have brain tumors, movement disorders or other neurological diseases.

Movement disorders are an area of specialized focus for our researchers. The program remains committed to bringing as many Parkinson's disease clinical trials and studies to Overlook Medical Center as possible, understanding the complexity of the condition and the diverse needs of these patients.

Our physicians are also highly involved in pediatric and adolescent neuroscience research, with particular expertise in identifying the genetic and environmental risk factors that contribute to Tourette's syndrome and autism. Discoveries in these fields have helped improve diagnostic guidelines and aided in the development of both medicinal and alternative therapies for these conditions.

Currently, we are conducting clinical trials and studies in the following conditions: Parkinson's disease, cervical dystonia, Tourette syndrome, autism, brain tumors, pseudobulbar affect (PBA), and stroke.

Our Physician Researchers

Oncology

Carol G. Simon Cancer Center at Morristown Medical Center and Overlook Medical Center is recognized as a leader in the diagnosis and treatment of all types of cancers. From innovative therapies and advanced diagnostics to minimally invasive surgery and the latest in radiation therapy, we offer cutting-edge medical technology, ground-breaking treatment techniques and exceptional support services in a comfortable setting.

For more than 20 years, our medical centers have participated in numerous clinical trials of investigational drugs and therapies that eventually received U.S. Food and Drug Administration (FDA) approval. From key developments in targeted therapy within breast and ovarian cancers to the use of immunotherapy and gene therapy to treat skin cancer, our physician investigators work in partnership with industry and cooperative group sponsors to bring the latest developments in cancer care to the community.

The growth of our cancer program reflects not only the growth of our medical centers, but also how differently cancer is treated today. Research into genetic and lifestyle factors that contribute to cancer has dramatically changed the way doctors and patients approach a cancer diagnosis.

We routinely offer clinical trials in many areas of cancer. Depending on the condition, trials are available in immunotherapy, gene therapy, radiation oncology, and oral and intravenous therapies. Many of our trials address metastatic and advanced disease, including:

  • Women's Cancers (Breast, Cervical, Endometrial & Ovarian)
  • Skin Cancers & Melanoma
  • Blood Cancers (Leukemia)
  • Colorectal, Pancreatic, Kidney & Liver Cancers
  • Prostate Cancer

Our Physician Researchers

Pediatrics

The name "children's hospital" is an earned recognition, meaning the hospital has met the standards of pediatric health care as defined by the national Children's Hospital Association and the State of New Jersey. This distinction signifies that we have multiple specialties that other general hospitals do not have, such as a pediatric intensive care unit and regional perinatal center, and that we actively participate in training and research.

Our academic environment, with a focus on critical thinking and research, not only allows us to help train the next generation of physicians, but also brings cutting-edge approaches to diagnosis and treatment that benefit our patients and families.

Physician investigators at Goryeb Children's Hospital have extensive experience in cancer and blood disorders, lung disease, gastrointestinal disease, hormonal and metabolic disorders, and neurological disorders. Our specialized centers are continuously improving outcomes through quality clinical care, research, education and full family support.

Primary research areas at our children's hospital include the following conditions:

  • Cancer and blood disorders
  • Cystic fibrosis
  • Crohn's disease and ulcerative colitis
  • Diabetes
  • Growth and puberty disorders
  • Autism, Tourette syndrome and other movement disorders (through partnership with Atlantic Neuroscience Institute)

The Valerie Fund Children's Center, part of the Division of Pediatric Hematology and Oncology at Goryeb Children's Hospital, provides personalized, comprehensive medical care to children, adolescents and young adults with cancer and blood disorders. The Valerie Fund Children's Center is a nationally recognized cancer center and active member of the Children's Oncology Group, the largest cooperative cancer group for patients under 21. Our participation in this group ensures that clinical trials and the latest research findings are always made available to our patients.

For information on clinical trials for pediatric cancer, please visit Children's Oncology Group.

Our Physician Researchers

Other Research Areas

At Atlantic Health System medical centers, the following departments are actively exploring new treatments, diagnostic techniques, and systems of care delivery. Research partnerships and collaborations with other health care systems and universities provide access to the most up-to-date data sharing platforms and latest findings.

Atlantic Sports Health

  • Concussion (diagnostics, recovery and management)
  • Joint and muscle pain
  • Lifestyle intervention and cancer survivorship programs
  • Exercise programs for children
  • Vitamin D deficiencies and bone mineral density
  • Omega 3 fatty acids in brain injuries

Institute for Rheumatic and Autoimmune Diseases (IRAD)

  • Biomarkers of anti-TNF therapies
  • Inflammatory arthritis (including rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis)
  • Lupus
  • Sjögren's syndrome
  • Osteoarthritis and osteoporosis

Atlantic Urogynecology Associates

  • Uterovaginal prolapse and genetic predisposition for pelvic organ prolapse
  • Urinary incontinence and overactive bladder
  • Electrical field stimulation and minimally invasive surgeries
  • Sexual and bowel function after laparoscopic surgeries

Wound Healing

  • Healing technologies for venous ulcers

Participating in Clinical Trials

A clinical trial (also called clinical research) is a research study using human volunteers to answer specific questions about medications and procedures. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments.

Every clinical trial has specific guidelines about participant qualifications. To standardize the test results, researchers use inclusion and exclusion criteria such as age, gender, the type and stage of a disease, previous treatment history and other medical conditions.

Some research studies seek participants with illnesses or conditions to be studied in the clinical trial, while others need healthy participants. Inclusion and exclusion criteria are not used to reject people personally, but to identify appropriate participants and keep them safe. The criteria help ensure that researchers will be able to answer the questions they plan to study.

A control group of people often provides the standard by which experimental observations are evaluated. In many clinical trials, one group of patients will be given an experimental drug or treatment, while the control group is given either a standard treatment for the illness or a placebo.

When you learn everything you can about a trial and still decide to participate, you are giving consent to be studied.

Medical staff will strive to ensure that you understand the ramifications of the treatment protocol. The research team will provide you with a consent document that includes details about the study, such as its purpose, duration, required procedures and key contacts. Risks and potential benefits are also explained in the consent document. A consent form is not a contract, and every participant is free to withdraw from the trial at any time.

Clinical trials are not intended to replace ongoing treatment with a primary physician. Most clinical trials provide short-term treatments related to a designated illness or condition, but do not provide extended or complete primary health care. Your health care provider will work with the research team to ensure that the trial protocol will not interfere with your other medications or treatments.